Objective of the SPASAK project is to pilot participatory SARS-CoV-2 animal surveillance with underserved Indigenous and non-Indigenous communities in Alaska using approaches that empower these communities to fully participate in disease surveillance (hunted animals, peri-domestic small mammals, domestic dogs, and wastewater), investigations, result communication, and potential response measures. Integrating social science methods will support the co-development of a scientifically, socially, and culturally acceptable surveillance system, from sampling to communication of findings, to participatory investigations on spillover mechanisms and interventions. Combining Indigenous knowledge with scientific understanding improves wildlife surveillance and advances Indigenous Peoples' (IP) self-d